HSD-016
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $2800 | To Be Confirmed |
| 200mg | $4200 | To Be Confirmed |
| 500mg | $7090 | To Be Confirmed |
: Cat #: V41925 CAS #: 946396-92-5 Purity ≥ 99%
Description: HSD-016 (HSD016) is a novel 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50 = 11, 1 and 8 nM for human, mouse and rat 11β-HSD1, respectively) with the potential to be used for type 2 diabetes.
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| Molecular Weight (MW) | 514.46 |
|---|---|
| Molecular Formula | C21H21F7N2O3S |
| CAS No. | 946396-92-5 |
| SMILES Code | O[C@](C(F)(F)F)(C)C1=CC=CC(S(=O)(N2[C@H](C)CN(C3=CC=C(F)C=C3C(F)(F)F)CC2)=O)=C1 |
| Synonyms | HSD-016; HSD 016; HSD016; HSD-16; HSD 16; HSD16; |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9438 mL | 9.7189 mL | 19.4379 mL | 38.8757 mL |
| 5mM | 0.3888 mL | 1.9438 mL | 3.8876 mL | 7.7751 mL |
| 10mM | 0.1944 mL | 0.9719 mL | 1.9438 mL | 3.8876 mL |
| 20mM | 0.0972 mL | 0.4859 mL | 0.9719 mL | 1.9438 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.