BVT-14225 is a novel and potent 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor.
AZD4017, a nicotinic amide derived carboxylic acid, is a novel, potent, selective and effective inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) in human adipocytes with an IC50 of 7 nM.
BMS-816336 is a potent and orally bioactive inhibitor of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme with an IC50 of 3.0 nM.
HSD-016 (HSD016) is a novel 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50 = 11, 1 and 8 nM for human, mouse and rat 11β-HSD1, respectively) with the potential to be used for type 2 diabetes.
Carbenoxolone sodium (Pyrogastrone; Biogastrone; Bioral; Duogastrone; Sanodin), an analogue of glycyrrhizin, is the active metabolite of Glycyrrhizic acid and an inhibitor of human 11β-HSD and bacterial 3α, 20β-HSD.