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Guggulsterone

This product is for research use only, not for human use. We do not sell to patients.

Guggulsterone
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$850To Be Confirmed
200mg$1275To Be Confirmed
500mg$2150To Be Confirmed
email: [email protected]        [email protected]

Cat #: V10614 CAS #: 95975-55-6 Purity ≥ 99%

Description: Guggulsterone (Guglip; Pregna-4,17(20)-diene-3,16-dione) is a potent and broad spectrum antagonist of steroid receptor ligand FXR with various biological activities.

References: Shishodia S, et al. Guggulsterone for Chemoprevention of Cancer. Curr Pharm Des. 2016;22(3):294-306.

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Molecular Weight (MW)312.45
Molecular FormulaC21H28O2
CAS No.95975-55-6
SMILES CodeO=C(C=C1CC[C@@]2([H])[C@]3([H])CC/4=O)CC[C@]1(C)[C@@]2([H])CC[C@]3(C)C4=C\C
SynonymsGuggulsterone; Guglip; Pregna-4,17(20)-diene-3,16-dione
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.2005 mL16.0026 mL32.0051 mL64.0102 mL
5mM0.6401 mL3.2005 mL6.4010 mL12.8020 mL
10mM0.3201 mL1.6003 mL3.2005 mL6.4010 mL
20mM0.1600 mL0.8001 mL1.6003 mL3.2005 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.