Golotimod (SCV07)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $450 | Check With Us |
| 500mg | $545 | Check With Us |
| 1g | $815 | Check With Us |
: Cat #: V18077 CAS #: 229305-39-9 Purity ≥ 98%
Description: Golotimod (Orilotimod, SCV-07), is a potent and orally bioavailable synthetic peptide with an immunomodulating and antimicrobial activities.
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| Molecular Weight (MW) | 333.34 |
|---|---|
| Molecular Formula | C16H19N3O5 |
| CAS No. | 229305-39-9 |
| SMILES Code | O=C(O)[C@H](N)CCC(N[C@H](C(O)=O)CC1=CNC2=C1C=CC=C2)=O |
| Synonyms | SCV 07; SCV-07; SCV07; gammaDglutamylLtryptophan. |
| Protocol | In Vitro | Golotimod (SCV-07) (oral gavage or subcutaneous injection, 100 μg/kg, 5 days) reduces experimental recurrent genital HSV-2 disease by oral administration, more importantly, oral SCV07 after fasting shows a greater reduction in incidence and severity than SCV-07 without fasting in female hartley guinea pigs. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.9999 mL | 14.9997 mL | 29.9994 mL | 59.9988 mL |
| 5mM | 0.6000 mL | 2.9999 mL | 5.9999 mL | 11.9998 mL |
| 10mM | 0.3000 mL | 1.5000 mL | 2.9999 mL | 5.9999 mL |
| 20mM | 0.1500 mL | 0.7500 mL | 1.5000 mL | 2.9999 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.