Glycolithocholic acid

This product is for research use only, not for human use. We do not sell to patients.

Glycolithocholic acid
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1600To Be Confirmed
200mg$2400To Be Confirmed
500mg$4050To Be Confirmed

Cat #: V21675 CAS #: 474-74-8 Purity ≥ 99%

Description: Glycolithocholic acid (Lithocholic acid glycine conjugate; Lithocholylglycine) is a glycine conjugate (N-acylglycine) of lithocholic acid which is a secondary bile acid.

References: Tanno N, et, al. Biliary lipid composition in heterozygous familial hypercholesterolemia and influence of treatment with probucol. Dig Dis Sci. 1994 Jul;39(7):1586-91.

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Molecular Weight (MW)433.62
Molecular FormulaC26H43NO4
CAS No.474-74-8
SMILES CodeO=C(O)CNC(CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
SynonymsGlycolithocholic acid; Lithocholylglycine; Lithocholic acid glycine conjugate;
ProtocolIn VivoThe concentrations of Glycolithocholic acid in ulcerative colitis (UC) patients were significantly lower than those in healthy controls (HCs).
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3062 mL11.5308 mL23.0617 mL46.1233 mL
5mM0.4612 mL2.3062 mL4.6123 mL9.2247 mL
10mM0.2306 mL1.1531 mL2.3062 mL4.6123 mL
20mM0.1153 mL0.5765 mL1.1531 mL2.3062 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
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Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.