Glycolithocholic acid
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
100mg | $1600 | To Be Confirmed |
200mg | $2400 | To Be Confirmed |
500mg | $4050 | To Be Confirmed |
Cat #: V21675 CAS #: 474-74-8 Purity ≥ 99%
Description: Glycolithocholic acid (Lithocholic acid glycine conjugate; Lithocholylglycine) is a glycine conjugate (N-acylglycine) of lithocholic acid which is a secondary bile acid.
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Molecular Weight (MW) | 433.62 |
---|---|
Molecular Formula | C26H43NO4 |
CAS No. | 474-74-8 |
SMILES Code | O=C(O)CNC(CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O |
Synonyms | Glycolithocholic acid; Lithocholylglycine; Lithocholic acid glycine conjugate; |
Protocol | In Vivo | The concentrations of Glycolithocholic acid in ulcerative colitis (UC) patients were significantly lower than those in healthy controls (HCs). |
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These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.3062 mL | 11.5308 mL | 23.0617 mL | 46.1233 mL |
5mM | 0.4612 mL | 2.3062 mL | 4.6123 mL | 9.2247 mL |
10mM | 0.2306 mL | 1.1531 mL | 2.3062 mL | 4.6123 mL |
20mM | 0.1153 mL | 0.5765 mL | 1.1531 mL | 2.3062 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.