Gemfibrozil

This product is for research use only, not for human use. We do not sell to patients.

Gemfibrozil
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10g$450Check With Us
25g$560Check With Us
50g$840Check With Us

Cat #: V0835 CAS #: 25812-30-0 Purity ≥ 99%

Description: Gemfibrozil (Pilder; CI-719; CI719; CI 719; Lopid; Jezil; Lipur; Trialmin) is a potent anti-hypertriglyceridemic/lipid lowering drug acting as an activator/agonist of peroxisome proliferator-activated receptor-alpha (PPARα).

References: Pahan K, et al. Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric-oxide synthase in human astrocytes. J Biol Chem. 2002 Nov 29;277(48):45984-91. Epub 2002 Sep 18.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)250.33
Molecular FormulaC15H22O3
CAS No.25812-30-0
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 50 mg/mL (199.7 mM)r
Water: <1 mg/mLr
Ethanol: 50 mg/mL (199.7 mM)
Solubility In Vivo
SMILES CodeCC1=CC(=C(C=C1)C)OCCCC(C)(C)C(=O)O
SynonymsPilder; PMS Gemfibrozil; CI-719; CI719; CI 719; PMS-Gemfibrozil; Gemfibrozil; Lopid; 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid; Jezil; Lipur; Trialmin; SBPA Gemfibrozil
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.9947 mL19.9736 mL39.9473 mL79.8945 mL
5mM0.7989 mL3.9947 mL7.9895 mL15.9789 mL
10mM0.3995 mL1.9974 mL3.9947 mL7.9895 mL
20mM0.1997 mL0.9987 mL1.9974 mL3.9947 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.