Gardiquimod
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $850 | To Be Confirmed |
| 500mg | $1400 | To Be Confirmed |
| 1g | $2100 | To Be Confirmed |
: Cat #: V21515 CAS #: 1020412-43-4 Purity ≥ 98%
Description: Gardiquimod, an imidazoquinoline compound, is a novel, potent and specific agonist of TLR7 (toll-like receptor 7) with antitumor and immunomodulatory effects.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 313.40 |
|---|---|
| Molecular Formula | C17H23N5O |
| CAS No. | 1020412-43-4 |
| SMILES Code | CC(O)(C)CN1C(CNCC)=NC2=C1C3=CC=CC=C3N=C2N |
| Synonyms | Gardiquimod |
| Protocol | In Vitro | Gardiquimod (6-60 μM ) significantly inhibits cDNA synthesis by HIV-1 reverse transcriptase. |
|---|---|---|
| In Vivo | Dendritic cells (DCs) in combination with Gardiquimod (1 mg/kg per mouse; i.p.; daily for 7 days) improves the anti-tumor effects of NK cells. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.1908 mL | 15.9541 mL | 31.9081 mL | 63.8162 mL |
| 5mM | 0.6382 mL | 3.1908 mL | 6.3816 mL | 12.7632 mL |
| 10mM | 0.3191 mL | 1.5954 mL | 3.1908 mL | 6.3816 mL |
| 20mM | 0.1595 mL | 0.7977 mL | 1.5954 mL | 3.1908 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.