flurbiprofen
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $450 | To Be Confirmed |
| 10g | $750 | To Be Confirmed |
| 20g | $1125 | To Be Confirmed |
: Cat #: V4881 CAS #: 5104-49-4 Purity ≥ 98%
Description: Flurbiprofen, a phenylalkanoic acid derivative, belongs to the class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs) with antipyretic and analgesic activity.
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| Molecular Weight (MW) | 244.26 |
|---|---|
| Molecular Formula | C15H13FO2 |
| CAS No. | 5104-49-4 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | CC(C1=CC=C(C2=CC=CC=C2)C(F)=C1)C(O)=O |
| Synonyms | Flurbiprofen, Ansaid, Froben, Cebutid, Antadys |
| Protocol | In Vitro | Flurbiprofen (10 nM; 24 hours) promotes the apoptosis of colorectal cancer cells by inhibiting COX-2. Flurbiprofen (10 nM; 24 hours) decreases COX-2 expression. Flurbiprofen (2-20 nM; 12-48 hours) significantly decreases SW620 cells proliferation in a concentration- and time-dependent manner. Flurbiprofen (10 nM; 24 hours) inhibits the expression of inflammatory factors by inhibiting COX-2. |
|---|---|---|
| In Vivo | Flurbiprofen (0.3-4.8 mg/kg; p.o.; 4-5 dosages) has acute anti-inflammatory in adrenalectomized rats. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.0940 mL | 20.4700 mL | 40.9400 mL | 81.8800 mL |
| 5mM | 0.8188 mL | 4.0940 mL | 8.1880 mL | 16.3760 mL |
| 10mM | 0.4094 mL | 2.0470 mL | 4.0940 mL | 8.1880 mL |
| 20mM | 0.2047 mL | 1.0235 mL | 2.0470 mL | 4.0940 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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Molecular Weight*
The dilution calculator equation
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Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.