Flubendazole (Flutelmium)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
10g	$320	Check With Us
50g	$980	Check With Us
100g	$1470	Check With Us

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Cat #: V1845 CAS #: 31430-15-6 Purity ≥ 98%

Description: Flubendazole (formerly also known as Flumoxanal, NSC 313680), an efficacious anti-helmintic drug widely used as an anti-helmintic for human, rodents and ruminants, is an autophagy inducer by targeting Atg4B, it is used to treat internal parasite and worm infection.

References: Michaelis M, et al. Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen. Sci Rep. 2015 Feb 3;5:8202.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	313.28
Molecular Formula	C16H12FN3O3
CAS No.	31430-15-6
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 3 mg/mL (9.6 mM)r
	Water: <1 mg/mLr
	Ethanol: <1 mg/mL
SMILES Code	O=C(OC)NC1=NC2=CC(C(C3=CC=C(F)C=C3)=O)=CC=C2N1
Synonyms	Flumoxanal, NSC 313680; NSC 313680; NSC313680; NSC-313680; R 17899; R17899; R-17899

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.1920 mL	15.9602 mL	31.9203 mL	63.8407 mL
5mM	0.6384 mL	3.1920 mL	6.3841 mL	12.7681 mL
10mM	0.3192 mL	1.5960 mL	3.1920 mL	6.3841 mL
20mM	0.1596 mL	0.7980 mL	1.5960 mL	3.1920 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.