Cabazitaxel-d6 is a deuterate form of cabazitaxel.
SR9009 (SR-9009; Stenabolic) is a novel and potent synthetic REV-ERBα/β agonist with the potential to be used for sleep disorders.
Brefeldin A (also known as BFA), a fungal metabolite, is a potent macrocyclic lactone antibiotic and ATPase inhibitor for intracellular vesicle formation and protein transport (protein trafficking between the endoplasmic reticulum (ER) and the Golgi apparatus) with IC50 of 0.2 μM in HCT 116 cells.
HOE 33342, formerly known as Hoechst 33342, HO342, is a Benzimidazole fluorescent dye and a Cell permeable fluorescent DNA stain; binds minor groove of AT-rich regions.
Spautin-1 is a specific autophagy inhibitor which inhibits the deubiquitinating activity of USP10 and USP13 with IC50 of ∼0.6-0.7 μM.
Schizandrin is a novel and potent agonist of the adiponectin receptor 2 (AdipoR2).
Aloe emodin (also known as NSC 38628, Rhabarberone; 3-Hydroxymethylchrysazine) is a hydroxyanthraquinone based and naturally occuring CFTR channel activator found in Aloe vera leaves, and has a specific in vitro and in vivo antitumor activity.
Rhein (also known as Monorhein; NSC 38629; Rheic acid; Rheinic acid) is a naturally occuring anthraquinone compound isolated from the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities.
Sophocarpine monohydrate, a major and naturally occuring ingredient found in Sophora alopecuroides, has a wide range of pharmacological effects.
Trifluoperazine dihydrochloride (TFP; SKF5019), a typical phenothiazine class of antipsychotic mainly used to treat schizophrenia, is a dopamine D2 receptor inhibitor with IC50 of 1.1 NM.