Flopropione
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $250 | Check With Us |
| 10g | $600 | Check With Us |
| 20g | $900 | Check With Us |
: Cat #: V1971 CAS #: 2295-58-1 Purity ≥ 98%
Description: Flopropione is a spasmolytic or antispasmodic agent, acting as a 5-HT1A receptor antagonist and also a catechol-o-methyltransferase (COMT) inhibitor.
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- Related Biological Data
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| Molecular Weight (MW) | 182.17 |
|---|---|
| Molecular Formula | C9H10O4 |
| CAS No. | 2295-58-1 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 36 mg/mL (197.61 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 36 mg/mL (197.61 mM) | |
| Synonyms | Argobyl; Chlonarin; Cospanon; Ecapron; Flopion; Flopropion; Gallepronin; Gasstenon; Labroda |
| Protocol | In Vivo | The effect of Flopropione as an antispasmodic agent on the rate of passing a calculus from the urinary tract has been compared retrospectively with patients in whom passage was spontaneous. Flopropine has been shown, with statistical significance, to be superior to the control in cumulative passage rate after initiation of administration. Flopropine has been shown to exert a spasmolytic effect not only on smooth muscle of the gastrointestinal tract but also on smooth muscle of the pancreatobiliary and urinary systems |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 5.4894 mL | 27.4469 mL | 54.8938 mL | 109.7876 mL |
| 5mM | 1.0979 mL | 5.4894 mL | 10.9788 mL | 21.9575 mL |
| 10mM | 0.5489 mL | 2.7447 mL | 5.4894 mL | 10.9788 mL |
| 20mM | 0.2745 mL | 1.3723 mL | 2.7447 mL | 5.4894 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.