Home > Signaling Pathways>PI3K/Akt/mTOR>PI3K>Fimepinostat (CUDC907)
Fimepinostat (CUDC907)

This product is for research use only, not for human use. We do not sell to patients.

Fimepinostat (CUDC907)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$859Check With Us
500mg$1180Check With Us
1g$1770Check With Us

Cat #: V0132 CAS #: 1339928-25-4 Purity ≥ 98%

Description: Fimepinostat (also known as CUDC-907) is a potent, orally bioavailable, and small molecule dual inhibitor of PI3K and HDAC (PI3Kα and HDAC1/2/3/10) with potential anticancer activity.

References: Qian C, et al. Cancer network disruption by a single molecule inhibitor targeting both histone deacetylase activity and phosphatidylinositol 3-kinase signaling. Clin Cancer Res. 2012 Aug 1;18(15):4104-13.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)508.55
Molecular FormulaC23H24N8O4S
CAS No.1339928-25-4
SMILES CodeO=C(C1=CN=C(N(CC2=CC3=NC(C4=CC=C(OC)N=C4)=NC(N5CCOCC5)=C3S2)C)N=C1)NO
SynonymsCUDC907; CUDC 907; CUDC-907; fimepinostat;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9664 mL9.8319 mL19.6637 mL39.3275 mL
5mM0.3933 mL1.9664 mL3.9327 mL7.8655 mL
10mM0.1966 mL0.9832 mL1.9664 mL3.9327 mL
20mM0.0983 mL0.4916 mL0.9832 mL1.9664 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.