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Famciclovir (BRL 42810)

This product is for research use only, not for human use. We do not sell to patients.

Famciclovir (BRL 42810)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$800Check With Us
10g$1350Check With Us
20g$2025Check With Us

Cat #: V5188 CAS #: 104227-87-4 Purity ≥ 98%

Description: Famciclovir (also known as BRL 42810) is a guanine class of antiviral drug used for the treatment of various herpesvirus infections, such as herpes zoster (shingles).

References: Wutzler P, Ulbricht A, Färber I. Antiviral efficacies of famciclovir, valaciclovir, and brivudin in disseminated herpes simplex virus type 1 infection in mice. Intervirology. 1997;40(1):15-21.

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Product Promise

Promise
Molecular Weight (MW)321.33
Molecular FormulaC14H19N5O4
CAS No.104227-87-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeCC(OCC(COC(C)=O)CCN1C=NC2=CN=C(N)N=C12)=O
SynonymsFamciclovir, Famvir, BRL-42810
ProtocolIn VitroFamciclovir metabolizes into BRL 42359 by deacetylation and then oxidizes to penciclovir.
In VivoFamciclovir (50-400 mg/kg; p.o. three times per day for total 10 doses) effectively cures necrotic hepatitis mice.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.1121 mL15.5603 mL31.1207 mL62.2413 mL
5mM0.6224 mL3.1121 mL6.2241 mL12.4483 mL
10mM0.3112 mL1.5560 mL3.1121 mL6.2241 mL
20mM0.1556 mL0.7780 mL1.5560 mL3.1121 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.