Famciclovir (BRL 42810)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
5g | $800 | Check With Us |
10g | $1350 | Check With Us |
20g | $2025 | Check With Us |
Cat #: V5188 CAS #: 104227-87-4 Purity ≥ 98%
Description: Famciclovir (also known as BRL 42810) is a guanine class of antiviral drug used for the treatment of various herpesvirus infections, such as herpes zoster (shingles).
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Molecular Weight (MW) | 321.33 |
---|---|
Molecular Formula | C14H19N5O4 |
CAS No. | 104227-87-4 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
SMILES Code | CC(OCC(COC(C)=O)CCN1C=NC2=CN=C(N)N=C12)=O |
Synonyms | Famciclovir, Famvir, BRL-42810 |
Protocol | In Vitro | Famciclovir metabolizes into BRL 42359 by deacetylation and then oxidizes to penciclovir. |
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In Vivo | Famciclovir (50-400 mg/kg; p.o. three times per day for total 10 doses) effectively cures necrotic hepatitis mice. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 3.1121 mL | 15.5603 mL | 31.1207 mL | 62.2413 mL |
5mM | 0.6224 mL | 3.1121 mL | 6.2241 mL | 12.4483 mL |
10mM | 0.3112 mL | 1.5560 mL | 3.1121 mL | 6.2241 mL |
20mM | 0.1556 mL | 0.7780 mL | 1.5560 mL | 3.1121 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.