F13714 fumarate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1450 | Check With Us |
| 250mg | $2500 | Check With Us |
| 500mg | $3750 | Check With Us |
: Cat #: V3527 CAS #: 208109-39-1 Purity ≥ 99%
Description: F-13714 fumarate (also known as F14679; F-14679) is a novel, potent and selective 5-HT1A receptor biased agonist with antidepressant-like properties.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 538.97 |
|---|---|
| Molecular Formula | C25H29ClF2N4O5 |
| CAS No. | 208109-39-1 |
| Protocol | In Vitro | F13714 targets 5-HT1A autoreceptors |
|---|---|---|
| In Vivo | In UCMS mice, a single administration of F13714 (4–16 mg/kg) is sufficient to robustly normalize depressive-like behavior in the forced swim test (FST). F13714 rescues cortical and hippocampal deficits in p-ERK1/2 levels but does not influence the p-CREB levels |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.8554 mL | 9.2770 mL | 18.5539 mL | 37.1078 mL |
| 5mM | 0.3711 mL | 1.8554 mL | 3.7108 mL | 7.4216 mL |
| 10mM | 0.1855 mL | 0.9277 mL | 1.8554 mL | 3.7108 mL |
| 20mM | 0.0928 mL | 0.4638 mL | 0.9277 mL | 1.8554 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.