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Ezetimibe phenoxy glucuronide

This product is for research use only, not for human use. We do not sell to patients.

Ezetimibe phenoxy glucuronide
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$3225To Be Confirmed
200mg$4840To Be Confirmed
500mg$8165To Be Confirmed
email: [email protected]        [email protected]

Cat #: V40057 CAS #: 190448-57-8 Purity ≥ 99%

Description: Ezetimibe phenoxy glucuronide (also called Ezetimibe glucuronide) is the active metabolite of Ezetimibe with antihyperlipoproteinemic activity.

References: Stolk MF, et al. Severe hepatic side effects of ezetimibe. Clin Gastroenterol Hepatol. 2006 Jul;4(7):908-11.

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Molecular Weight (MW)585.55
Molecular FormulaC30H29F2NO9
CAS No.190448-57-8
SynonymsEzetimibe phenoxy glucuronide
ProtocolIn VivoAfter oral administration, Ezetimibe is absorbed in the small intestine and more than 80% of Ezetimibe metabolized to Ezetimibe Glucuronide.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.7078 mL8.5390 mL17.0780 mL34.1559 mL
5mM0.3416 mL1.7078 mL3.4156 mL6.8312 mL
10mM0.1708 mL0.8539 mL1.7078 mL3.4156 mL
20mM0.0854 mL0.4269 mL0.8539 mL1.7078 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Volume(start)
V1
 
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.