Etilevodopa HCl

This product is for research use only, not for human use. We do not sell to patients.

Etilevodopa HCl
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Size Price Stock
25mg$1150Check With Us
50mg$1725Check With Us
100mg$2585Check With Us

Cat #: V20820 CAS #: 39740-30-2 Purity ≥ 99%

Description: Etilevodopa HCl (TV-1203; Levodopa ethyl ester; L-Dopa ethyl ester; O-Ethyl-DOPA), the hydrochloride salt of Etilevodopa, is a dopaminergic agent used for the treatment for Parkinson's disease.

References: Djaldetti R, et al. Pharmacokinetics of etilevodopa compared to levodopa in patients with Parkinson's disease: an open-label, randomized, crossover study. Clin Neuropharmacol. 2003 Nov-Dec;26(6):322-6.

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Molecular Weight (MW)261.702
Molecular FormulaC11H16ClNO4
CAS No.39740-30-2
SynonymsTV-1203; Levodopa ethyl ester; L-Dopa ethyl ester; O-Ethyl-DOPA
ProtocolIn VitroEtilevodopa (L-Dopa ethyl ester) hydrochloride passes unchanged through the stomach to the duodenum, where it is rapidly hydrolyzed by local esterases to Levodopa and ethanol, and is subsequently absorbed into the blood stream as Levodopa
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.8211 mL19.1057 mL38.2114 mL76.4228 mL
5mM0.7642 mL3.8211 mL7.6423 mL15.2846 mL
10mM0.3821 mL1.9106 mL3.8211 mL7.6423 mL
20mM0.1911 mL0.9553 mL1.9106 mL3.8211 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.