Esflurbiprofen

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
500mg	$550	To Be Confirmed
1g	$950	To Be Confirmed
5g	$2400	To Be Confirmed

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Cat #: V10613 CAS #: 51543-39-6 Purity ≥ 99%

Description: Esflurbiprofen (BTS-24332; TT 063; BTS24332; TT063; SFPP; BTS 24332; TT-063; Trade name: Loqoa), the S-enantiomrer or S-isomer of Flurbiprofen, is a potent cyclooxygenase (COX) inhibitor and a nonsteroidal anti-inflammatory drugs (NSAIDs) with antipyretic and analgesic activity.

References: A Carabaza, et al. Stereoselective Inhibition of Inducible Cyclooxygenase by Chiral Nonsteroidal Antiinflammatory Drugs. J Clin Pharmacol. 1996 Jun;36(6):505-12.

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Molecular Weight (MW)	244.26
Molecular Formula	C15H13FO2
CAS No.	51543-39-6
SMILES Code	O=C(O)[C@@H](C)C1=CC=C(C2=CC=CC=C2)C(F)=C1
Synonyms	BTS-24332; BTS 24332; BTS24332; TT-063; TT 063; TT063; SFPP; Esflurbiprofen. Trade name: Loqoa

Protocol	In Vitro	(S)-Flurbiprofen (10–7 M) results in a total suppression of basal and stimulated PGE2 release in rat skin.

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	4.0940 mL	20.4700 mL	40.9400 mL	81.8800 mL
5mM	0.8188 mL	4.0940 mL	8.1880 mL	16.3760 mL
10mM	0.4094 mL	2.0470 mL	4.0940 mL	8.1880 mL
20mM	0.2047 mL	1.0235 mL	2.0470 mL	4.0940 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.