Endoxifen HCl

This product is for research use only, not for human use. We do not sell to patients.

Endoxifen HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1250Check With Us
250mg$1950Check With Us
500mg$2975Check With Us

Cat #: V1728 CAS #: 1032008-74-4 Purity ≥ 98%

Description: Endoxifen HCl (Z-Endoxifen; N-Desmethyl-4-hydroxytamoxifen), the hydrochloride salt of endoxifen which is an active metabolite of Tamoxifen, is a potent and selective estrogen receptor antagonist/SERM with potential anticancer activity.

References: Chae YJ, et al. Endoxifen, the active metabolite of tamoxifen, inhibits cloned hERG potassium channels. Eur J Pharmacol. 2015 Apr 5;752:1-7.

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Product Promise

Promise
Molecular Weight (MW)409.95
Molecular FormulaC25H28ClNO2
CAS No.1032008-74-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 74 mg/mL (180.5 mM)r
Water: <1 mg/mLr
Ethanol: 74 mg/mL (180.5 mM)
SynonymsZ-Endoxifen HCl; 4-Hydroxy-N-desmethyltamoxifen; Endoxifen hydrochloride; N-Desmethyl-4-hydroxytamoxifen
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4393 mL12.1966 mL24.3932 mL48.7864 mL
5mM0.4879 mL2.4393 mL4.8786 mL9.7573 mL
10mM0.2439 mL1.2197 mL2.4393 mL4.8786 mL
20mM0.1220 mL0.6098 mL1.2197 mL2.4393 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.