Dyphylline

This product is for research use only, not for human use. We do not sell to patients.

Dyphylline
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Size Price Stock
25g$350Check With Us
50g$450Check With Us
100g$675Check With Us

Cat #: V0793 CAS #: 479-18-5 Purity ≥ 98%

Description: Dyphylline (also named as Diprophylline; Corphyllin; Lufyllin; Neothylline), a xanthine derivative with bronchodilator and vasodilator effects, is used in the treatment of respiratory disorders like cardiac dyspnea, asthma, and bronchitis.

References: Schwabe U, et al. Xanthine derivatives as antagonists at A1 and A2 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol. 1985 Sep;330(3):212-21.

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Molecular Weight (MW)254.24
Molecular FormulaC10H14N4O4
CAS No.479-18-5
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 51 mg/mL (200.6 mM)rr
Water:<1 mg/mLrr
Ethanol: 51 mg/mL (200.6 mM)
SMILES CodeCN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(CO)O
SynonymsDiprophylline; Dyphylline; Lufyllin; Corphyllin; Neothylline
ProtocolIn VitroDyphylline (trade names Dilor, Lufyllin), also known as diprophylline, is a xanthine derivative with bronchodilator and vasodilator effects. It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.9333 mL19.6665 mL39.3329 mL78.6658 mL
5mM0.7867 mL3.9333 mL7.8666 mL15.7332 mL
10mM0.3933 mL1.9666 mL3.9333 mL7.8666 mL
20mM0.1967 mL0.9833 mL1.9666 mL3.9333 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.