Dolasetron (MDL-73147)

This product is for research use only, not for human use. We do not sell to patients.

Dolasetron (MDL-73147)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$600To Be Confirmed
100mg$900To Be Confirmed
200mg$1350To Be Confirmed

Cat #: V15974 CAS #: 115956-12-2 Purity ≥ 98%

Description: Dolasetron (MDL-73147) is a potent serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

References: Faria C, et al. Outcomes Associated with 5-HT3-RA Therapy Selection in Patients with Chemotherapy-Induced Nausea and Vomiting: A Retrospective Claims Analysis. Am Health Drug Benefits. 2014 Jan;7(1):50-8.

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Product Promise

Promise
Molecular Weight (MW)324.37
Molecular FormulaC19H20N2O3
CAS No.115956-12-2
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.0829 mL15.4145 mL30.8290 mL61.6580 mL
5mM0.6166 mL3.0829 mL6.1658 mL12.3316 mL
10mM0.3083 mL1.5414 mL3.0829 mL6.1658 mL
20mM0.1541 mL0.7707 mL1.5414 mL3.0829 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.