Dipyridamole ( NSC-515776; RA-8; Persantine)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $250 | Check With Us |
| 25g | $450 | Check With Us |
| 50g | $675 | Check With Us |
: Cat #: V0790 CAS #: 58-32-2 Purity ≥ 99%
Description: Dipyridamole (also known as NSC515776; RA8; Persantine) is a pyrimido-pyrimidine based phosphodiesterase (PDE) inhibitor with antiplatelet properties.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 504.63 |
|---|---|
| Molecular Formula | C24H40N8O4 |
| CAS No. | 58-32-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 101 mg/mL (200.1 mM)r |
| Water:<1 mg/mLr | |
| Ethanol: 50 mg/mL (99.1 mM) | |
| SMILES Code | OCCN(CCO)C1=NC(N2CCCCC2)=C(N=C(N(CCO)CCO)N=C3N4CCCCC4)C3=N1 |
| Synonyms | Dipyridamine; NSC 515776; RA 8; NSC-515776; NSC515776; RA8; RA-8; Dipyridamole; Dipyridamol |
| Protocol | In Vitro | Dipyridamole (5 μM; 48 h) possesse cAMP/PKA-independent activity against statininduced SREBP2 activation. |
|---|---|---|
| In Vivo | Dipyridamole (10 mg/kg; p.o. once daily for 18 d) mitigates tumor growth, ameliorated concurrent alterations in blood circulation and tumor tissues, and platelet infiltration in tumor tissues. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9816 mL | 9.9082 mL | 19.8165 mL | 39.6330 mL |
| 5mM | 0.3963 mL | 1.9816 mL | 3.9633 mL | 7.9266 mL |
| 10mM | 0.1982 mL | 0.9908 mL | 1.9816 mL | 3.9633 mL |
| 20mM | 0.0991 mL | 0.4954 mL | 0.9908 mL | 1.9816 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.