This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 25g | $90 | 3-6 Days |
| 50g | $130 | 3-6 Days |
| 100g | $190 | 3-6 Days |
: Cat #: V29331 CAS #: 78213-16-8 Purity ≥ 99%
Description: Diclofenac diethylamine is a potent nonsteroidal anti-inflammatory drug (NSAID), acting as a non-selective COX inhibitor with IC50 of 0.5 μg/ml and 0.5 μg/ml for COX-1 and -2 in intact cells, respectively, used to relieve pain and reduce swelling in flammation. Diclofenac inhibits Wnt/beta-catenin signaling without altering the level of beta-catenin protein and reduces the expression of beta-catenin/TCF-dependent genes. Diclofenac induces the degradation of IkappaBalpha, which increases free nuclear factor kappaB (NF-kappaB) in colon cancer cells.
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| Molecular Weight (MW) | 369.2855 |
|---|---|
| Molecular Formula | C18H22CL2N2O2 |
| CAS No. | 78213-16-8 |
| Storage | Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Note: Please store this product in a sealed and protected environment, avoid exposure to moisture. |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.7079 mL | 13.5397 mL | 27.0793 mL | 54.1586 mL |
| 5mM | 0.5416 mL | 2.7079 mL | 5.4159 mL | 10.8317 mL |
| 10mM | 0.2708 mL | 1.3540 mL | 2.7079 mL | 5.4159 mL |
| 20mM | 0.1354 mL | 0.6770 mL | 1.3540 mL | 2.7079 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.