Dibucaine (Cinchocaine)

This product is for research use only, not for human use. We do not sell to patients.

Dibucaine (Cinchocaine)
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Size Price Stock
50g$480Check With Us
100g$800Check With Us
200g$1200Check With Us

Cat #: V19772 CAS #: 85-79-0 Purity ≥ 98%

Description: Dibucaine HCl (also known as Cinchocaine), a sodium channel inhibitor, is one of the most potent and toxic of the long-acting local anesthetics.

References: Souto-Padron, T., A.P. Lima, and O. Ribeiro Rde, Effects of dibucaine on the endocytic/exocytic pathways in Trypanosoma cruzi. Parasitol Res, 2006. 99(4): p. 317-20.

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Molecular Weight (MW)343.46
Molecular FormulaC20H29N3O2
CAS No.85-79-0
SynonymsDibucaine; Cinchocaine; Nupercainal; Nupercaine; Sovcaine; Dibucaine Base
ProtocolIn VitroDibucaine (Cinchocaine) reduces the degradation of BSA-gold complex in the reservosomes, which was not caused either by an inhibition of the whole proteolytic activity of the parasite or by a reduction on the expression levels of cruzipain
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9115 mL14.5577 mL29.1155 mL58.2309 mL
5mM0.5823 mL2.9115 mL5.8231 mL11.6462 mL
10mM0.2912 mL1.4558 mL2.9115 mL5.8231 mL
20mM0.1456 mL0.7279 mL1.4558 mL2.9115 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.