Deltarasin

This product is for research use only, not for human use. We do not sell to patients.

Deltarasin
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1050Check With Us
250mg$1600Check With Us
500mg$2400Check With Us

Cat #: V0784 CAS #: 1440898-61-2 Purity ≥ 98%

Description: Deltarasin (also known as Deltarasin hydrochloride) is a novel, high affinity and potent small molecule inhibitor of KRAS-PDEδ protein-protein interaction with potential antineoplastic activity.

References: Zimmermann G, et al. Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling. Nature. 2013 May 30;497(7451):638-42.

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Product Promise

Promise
Molecular Weight (MW)603.75
Molecular FormulaC40H37N5O
CAS No.1440898-61-2
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 100 mg/mL (165.6 mM)r
Water:<1 mg/mLr
Ethanol: <1 mg/L
SynonymsDeltarasin hydrochloride; Deltarasin HCl; Deltarasin;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.6563 mL8.2816 mL16.5631 mL33.1263 mL
5mM0.3313 mL1.6563 mL3.3126 mL6.6253 mL
10mM0.1656 mL0.8282 mL1.6563 mL3.3126 mL
20mM0.0828 mL0.4141 mL0.8282 mL1.6563 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.