Dehydroepiandrosterone (DHEA)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $200 | In Stock |
| 25g | $300 | In Stock |
| 50g | $450 | In Stock |
: Cat #: V1733 CAS #: 53-43-0 Purity ≥ 98%
Description: Dehydroepiandrosterone (trans-Dehydroandrosterone; DHEA; Prasterone; Psicosterone; EL-10; GL-701; IP-1001; NSC-9896; PB-007; SH-K-04828; Androstenolone; Diandrone) is an endogenous steroidal hormone acting as an androgen receptor antagonist and an estrogen receptor agonist.
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- Related Biological Data
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| Molecular Weight (MW) | 288.43 |
|---|---|
| Molecular Formula | C19H28O2 |
| CAS No. | 53-43-0 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 57 mg/mL (197.6 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 57 mg/mL (197.6 mM) | |
| Synonyms | NSC 9896; Prasterone; Psicosterone; DHEA; EL-10; GL-701; EL10; GL701; EL 10; GL 701; IP-1001; NSC-9896; IPL1001; NSC 896; IPL 1001; PB-007; SH-K-04828; Androstenolone; Diandrone; |
| Protocol | In Vivo | DHEA (Prasterone) in the diet (0.45 % w/w) of male B6 mice (groups of five mice) treated for 8 weeks led to significant decreases in body temperature compared with mice fed the control AIN-76A diet. A similar comparison indicated that control and pair-fed mice are also significantly different. Animals fed DHEA (Prasterone) have significantly lower temperatures than mice fed the control diet 26/29 times tested; mice pair fed to those on the DHEA (Prasterone) diet are less affected, with 8/29 values significantly lower than in mice fed AIN-76A ad libitum. The temperatures of mice fed DHEA (Prasterone) or pair fed to DHEA (Prasterone) are significantly different 21/29 times tested. Body weights are significantly greater in mice fed the control diet than in mice fed DHEA or pair fed to DHEA (Prasterone). Food intake (grams per day) from cages are averaged for each week (n=7), except for Week 9 (n=3). The amount of food intake is significantly decreased in mice fed DHEA (Prasterone). By design, mice pair fed to DHEA (Prasterone) ate about the same amount. Thus, it appears that DHEA (Prasterone) reduces body temperature by food restriction and by a separate mechanism |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.4670 mL | 17.3352 mL | 34.6705 mL | 69.3409 mL |
| 5mM | 0.6934 mL | 3.4670 mL | 6.9341 mL | 13.8682 mL |
| 10mM | 0.3467 mL | 1.7335 mL | 3.4670 mL | 6.9341 mL |
| 20mM | 0.1734 mL | 0.8668 mL | 1.7335 mL | 3.4670 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.