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| Size | Price | Stock |
|---|---|---|
| 250mg | $450 | Check With Us |
| 500mg | $700 | Check With Us |
| 1g | $1050 | Check With Us |
: Cat #: V19220 CAS #: 1425485-72-8 Purity ≥ 99%
Description: DBCO-C6-acid, an analog of DBCO-Acid with an extended 6-carbon atom spacer arm, is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues.
References: [1]. Almaliti J, et al. Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents.
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- Related Biological Data
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| Molecular Weight (MW) | 333.38 |
|---|---|
| Molecular Formula | C21H19NO3 |
| CAS No. | 1425485-72-8 |
| Solubility In Vitro | DMSO : 100 mg/mL (299.96 mM; Need ultrasonic) |
| SMILES Code | O=C(CCCCC(O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3 |
| Synonyms | DBCO-C6-acid |
| Protocol | In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
|---|
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.9996 mL | 14.9979 mL | 29.9958 mL | 59.9916 mL |
| 5mM | 0.5999 mL | 2.9996 mL | 5.9992 mL | 11.9983 mL |
| 10mM | 0.3000 mL | 1.4998 mL | 2.9996 mL | 5.9992 mL |
| 20mM | 0.1500 mL | 0.7499 mL | 1.4998 mL | 2.9996 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.