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CTP354

This product is for research use only, not for human use. We do not sell to patients.

CTP354
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Size Price Stock
250mg$1100Check With Us
500mg$1750Check With Us
1g$2625Check With Us
email: [email protected]        [email protected]

Cat #: V18855 CAS #: 1213669-91-0 Purity ≥ 98%

Description: CTP354, formerly known as C-21191, a novel deuterated subtype-selective GABA(A) modulator. CTP may be potentially useful for treatment of neuropathic pain, spasticity and anxiety disorders.

References: Hofmann M, et al. Assessment of the effects of NS11394 and L-838417, α2/3 subunit-selective GABA(A) [corrected] receptor-positive allosteric modulators, in tests for pain, anxiety, memory and motor function [published correction appears in Behav Pharmacol. 2013 Apr;24(2):153]. Behav Pharmacol. 2012;23(8):790-801.

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Molecular Weight (MW)408.46072
Molecular FormulaC19H10D9F2N7O
CAS No.1213669-91-0
SynonymsCTP354; CTP-354; CTP 354; C-21191; C 21191; C21191.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4482 mL12.2411 mL24.4822 mL48.9643 mL
5mM0.4896 mL2.4482 mL4.8964 mL9.7929 mL
10mM0.2448 mL1.2241 mL2.4482 mL4.8964 mL
20mM0.1224 mL0.6121 mL1.2241 mL2.4482 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.