CTB

This product is for research use only, not for human use. We do not sell to patients.

CTB
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1250Check With Us
500mg$1950Check With Us
1g$2925Check With Us

Cat #: V3344 CAS #: 451491-47-7 Purity ≥ 99%

Description: CTB (also known as Cholera Toxin B subunit) is a potent activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells.

References: Mantelingu K, et al. Activation of p300 histone acetyltransferase by small molecules altering enzyme structure: probed by surface-enhanced Raman spectroscopy. J Phys Chem B. 2007;111(17):4527-4534. 

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)343.73
Molecular FormulaC16H13ClF3NO2
CAS No.451491-47-7
SMILES CodeO=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=CC=CC=C2OCC
Synonyms Cholera Toxin B subunit
ProtocolIn VitroCTB (10, 50, 100, 150, 200, and 250 µM; 10 min) enhances p300 HAT activity of p300 in a dosedependent manner.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9093 mL14.5463 mL29.0926 mL58.1852 mL
5mM0.5819 mL2.9093 mL5.8185 mL11.6370 mL
10mM0.2909 mL1.4546 mL2.9093 mL5.8185 mL
20mM0.1455 mL0.7273 mL1.4546 mL2.9093 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.