Anacardic Acid (Hydroginkgolic acid), a natural product isolated from cashew nut shell liquid, is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases, which also has antibacterial activity, antimicrobial activity, prostaglandin synthase inhibition, and tyrosinase and lipoxygenase inhibition.

TTK-21 is a novel activator of CBP/p300 histone acetyltransferase activity.

WM-3835 (WM3835) is a novel and potent lysine acetyltransferase HBO1 (KAT7) inhibitor with potential anticancer activity. It binds directly to the acetyl-CoA binding site of HBO1 33. HBO1 (KAT7 or MYST2) is a histone acetyltransferase that acetylates H3 and H4 histones. HBO1 overexpression promotes OS cell growth in vitro and in vivo. WM-3835 was able […]

I-CBP112 ( I-CBP-112) is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor (PPI) with anticancer activity.

CTB (also known as Cholera Toxin B subunit) is a potent activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells.

Ranolazine (formerly CVT-303, RS 43285-003; brand name Ranexa) is a approved anti-angina drug used to treat chronic angina.

Remodelin HBr, the hydrobromide salt of Remodelin and a cell-permeable and stable analog of CPTH2, is an acetyl-transferase NAT10 inhibitor.

Curcumin (Diferuloylmethane; NSC32982; Turmeric Yellow; curcumin I) is a naturally occurring diarylheptanoid diarylheptanoid with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities.

Remodelin is a novel, selective and potent acetyl-transferase NAT10 inhibitor that is cell-permeable and stable analog of CPTH2.

MG-149 (MG149) is a novel, potent and selective histone acetyltransferase (HAT) inhibitor with anticancer activity.