Clomifene citrate (Clomiphene)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
10g	$165	Check With Us
100g	$900	Check With Us
200g	$1350	Check With Us

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Cat #: V1740 CAS #: 50-41-9 Purity ≥ 98%

Description: Clomifene Citrate (NSC35770; NSC-35770; Omifin; Chloramiphene; Clomide; Clostilbegit; Clomid; Androxal; Dyneric; Gravosan; Klostilbegit; Serophene), the citrate salt of Clomifene, is a potent SERM (selective estrogen receptor modulator) that has been used in the treatment of ovulation induction.

References: Kurosawa, T., et al., Clomiphene citrate elicits estrogen agonistic/antagonistic effects differentially via estrogen receptors alpha and beta. Endocr J, 2010. 57(6): p. 517-21.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	598.08
Molecular Formula	C26H28ClNO.C6H8O7
CAS No.	50-41-9
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 120 mg/mL (200.6 mM)r
	Water: <1 mg/mLr
	Ethanol: 11 mg/mL (18.4 mM)
Solubility In Vivo	Chemical Name: 2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanamine InChi Key: GKIRPKYJQBWNGO-QPLCGJKRSA-N InChi Code: InChI=1S/C26H28ClNO/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23/h5-18H,3-4,19-20H2,1-2H3/b26-25- SMILES Code: CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3
Synonyms	NSC-35770; Clomiphene; D; Chloramiphene; NSC35770; NSC 35770; Omifin; Citrate; Clomiphene; Clomide; Clomifen; Clostilbegit; Clomid; Androxal; Dyneric; Gravosan; Klostilbegit; Serophene

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.6720 mL	8.3601 mL	16.7202 mL	33.4403 mL
5mM	0.3344 mL	1.6720 mL	3.3440 mL	6.6881 mL
10mM	0.1672 mL	0.8360 mL	1.6720 mL	3.3440 mL
20mM	0.0836 mL	0.4180 mL	0.8360 mL	1.6720 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.