Cisapride
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
500mg | $400 | Check With Us |
1g | $650 | Check With Us |
5g | $1775 | Check With Us |
Cat #: V11877 CAS #: 81098-60-4 Purity ≥ 99%
Description: Cisapride (formerly R51619; R 51619; R-51619; Kaudalit; Prepulsid; Kinestase; Pridesia; Presid; Propulsid) is a benzamide-based nonselective agonist of serotonin 5-HT4 receptor.
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- Related Biological Data
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Molecular Weight (MW) | 465.95 |
---|---|
Molecular Formula | C23H29ClFN3O4 |
CAS No. | 81098-60-4 |
Protocol | In Vivo | Cisapride (2 mg/kg, (intraperitoneal); 4 mg/kg, (oral); Once) There were no significant differences in macroscopic features, histopathological features, cytokine profiles, and body weight changes in rats treated with trinitrobenzenesulfonic acid |
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Animal model | Male Wistar rats with trinitrobenzenesulfonic-acid-(TNBS) induced rat colitis | |
Dosages | 2 mg/kg (i.p.); 4 mg/kg, (oral administration) | |
Administration | 2 mg/kg, intraperitoneal injection ; 4 mg/kg, oral administration; once |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.1462 mL | 10.7308 mL | 21.4615 mL | 42.9231 mL |
5mM | 0.4292 mL | 2.1462 mL | 4.2923 mL | 8.5846 mL |
10mM | 0.2146 mL | 1.0731 mL | 2.1462 mL | 4.2923 mL |
20mM | 0.1073 mL | 0.5365 mL | 1.0731 mL | 2.1462 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.