Ciprofibrate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $450 | Check With Us |
| 5g | $850 | Check With Us |
| 10g | $1275 | Check With Us |
: Cat #: V0833 CAS #: 52214-84-3 Purity ≥ 98%
Description: Ciprofibrate (BRN-1984981; CCRIS 173; CCRIS173; Win-35833; BRN 1984981; BRN1984981;CCRIS-173) is a potent and selective agonist of PPAR/peroxisome proliferator-activated receptor agonist with antilipidemic activity.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 289.15 |
|---|---|
| Molecular Formula | C13H14Cl2O3 |
| CAS No. | 52214-84-3 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 58 mg/mL (200.6 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 58 mg/mL (200.6 mM) | |
| SMILES Code | CC(C)(OC1=CC=C(C2C(Cl)(Cl)C2)C=C1)C(O)=O |
| Synonyms | BRN-1984981; CCRIS 173; CCRIS173; Win-35833; BRN 1984981; BRN1984981;CCRIS-173; Ciprofibrate; WIN 35833; WIN35833 |
| Protocol | In Vitro | Ciprofibrate (500 μM; 4 hours) increases the PPARa phosphorylation level in rat Fao cells. |
|---|---|---|
| In Vivo | Ciprofibrate (oral administration; 10 mg/kg/day; 3 days) does not result in any significant effects on body weight or absolute liver weight for MCD diet-fed mice. Ciprofibrate improves hepatic steatosis and reduced hepatic necro-inflammation in MCD diet-fed mice. It also reduced hepatic cytokine protein and mRNA levels (MCP-1, TNFα and IL-6) as compared to those of choline-deficient (MCD) diet-fed mice. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.4584 mL | 17.2921 mL | 34.5841 mL | 69.1683 mL |
| 5mM | 0.6917 mL | 3.4584 mL | 6.9168 mL | 13.8337 mL |
| 10mM | 0.3458 mL | 1.7292 mL | 3.4584 mL | 6.9168 mL |
| 20mM | 0.1729 mL | 0.8646 mL | 1.7292 mL | 3.4584 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.