Cidofovir (GS 0504)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $450 | V1444 |
| 1g | $645 | V1444 |
| 5g | $1635 | V1444 |
: Cat #: V1444 CAS #: 113852-37-2 Purity ≥ 98%
Description: Cidofovir (also known as HPMPC; GS-0504; HPMPC; (S)-HPMPC; Vistide) is a potent and injectable antiviral medication approved for the treatment of cytomegalovirus (CMV) retinitis with IC50 of 0.94 μM.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 279.19 |
|---|---|
| Molecular Formula | C8H14N3O6P |
| CAS No. | 113852-37-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: <1 mg/mLr |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| Synonyms | HPMPC; Cidofovir; GS-504; GS 504; Vistide; HPMPC; (S)-HPMPC; GS-504. |
| Protocol | In Vitro | Cidofovir (5-100 μM, 72 hours) has antiviral activity against feline herpesvirus type-1 (FHV-1) with an IC50 of 11 μM, and can reduce Crandell-Reese feline kidney cell counts in a dose-dependent manner |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.5818 mL | 17.9090 mL | 35.8179 mL | 71.6358 mL |
| 5mM | 0.7164 mL | 3.5818 mL | 7.1636 mL | 14.3272 mL |
| 10mM | 0.3582 mL | 1.7909 mL | 3.5818 mL | 7.1636 mL |
| 20mM | 0.1791 mL | 0.8954 mL | 1.7909 mL | 3.5818 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.