Chenodeoxycholic Acid

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
50g	$300	Check With Us
100g	$400	Check With Us
200g	$600	Check With Us

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Cat #: V17434 CAS #: 474-25-9 Purity ≥ 99%

Description: Chenodeoxycholic acid (Anthropodesoxycholic acid; Anthropodeoxycholic acid) is a naturally occurring bile acid (found in the body) acting as an apoptosis inducer via PKC-dependent signalling pathway.

References: Stauffer AT, et al. Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor. J Biol Chem. 2002 Jul 19;277(29):26286-92

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Molecular Weight (MW)	392.57
Molecular Formula	C24H40O4
CAS No.	474-25-9
SMILES Code	C[C@@H]([C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O
Synonyms	Chenodeoxycholic Acid; Anthropodeoxycholic acid; Anthropodesoxycholic acid; CCRIS 2195; Chendol; chenic acid; Chenix; Chenodeoxycholic acid; Chenodesoxycholic acid; Chenodiol; Gallodesoxycholic acid; NSC 657949; Xenbilox

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.5473 mL	12.7366 mL	25.4732 mL	50.9463 mL
5mM	0.5095 mL	2.5473 mL	5.0946 mL	10.1893 mL
10mM	0.2547 mL	1.2737 mL	2.5473 mL	5.0946 mL
20mM	0.1274 mL	0.6368 mL	1.2737 mL	2.5473 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.