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CD40-TRAF6 inhibitor

This product is for research use only, not for human use. We do not sell to patients.

CD40-TRAF6 inhibitor
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$450To Be Confirmed
250mg$700To Be Confirmed
500mg$1050To Be Confirmed

Cat #: V17766 CAS #: 433249-94-6 Purity ≥ 99%

Description: CD40-TRAF6 inhibitor (TRAF-STOP inhibitor 6877002) is a novel and potent inhibitor of CD40-TRAF6 protein protein interaction with the potential for treating atherosclerosis.

References: Seijkens TTP, et al. Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis. J Am Coll Cardiol. 2018 Feb 6;71(5):527-542.

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Product Promise

Promise
Molecular Weight (MW)251.32
Molecular FormulaC17H17NO
CAS No.433249-94-6
SMILES CodeO=C(/C=C/NC1=C(C)C=CC(C)=C1)C2=CC=CC=C2
SynonymsCD40-TRAF6 inhibitor; CD40 TRAF6 inhibitor; TRAF-STOP 6877002; SMI-6877002; CD40-TRAF6 inhibitor 6877002; SMI 6877002; SMI6877002
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.9790 mL19.8950 mL39.7899 mL79.5798 mL
5mM0.7958 mL3.9790 mL7.9580 mL15.9160 mL
10mM0.3979 mL1.9895 mL3.9790 mL7.9580 mL
20mM0.1989 mL0.9947 mL1.9895 mL3.9790 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.