Calcium Levofolinate ( Calcium levofolinate; CL307782)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $480 | Check With Us |
| 25g | $850 | Check With Us |
| 50g | $1275 | Check With Us |
: Cat #: V2074 CAS #: 80433-71-2 Purity ≥ 98%
Description: Calcium Levofolinate (also known as Calcium Folinate; Calcium levofolinate; CL307782), a calcium salt of and the enantiomerically active form of folinic acid, is widely used as an adjuvant in cancer chemotherapy, e.g.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 511.5 |
|---|---|
| Molecular Formula | C20H21N7O7.Ca |
| CAS No. | 80433-71-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: <1 mg/mLr |
| Water: 9 mg/mL (17.6 mM)r | |
| Ethanol: <1 mg/mL | |
| Synonyms | Calcium Folinate; Calcium levofolinate; CL307782; CL 307782; CL-307782 |
| Protocol | In Vivo | Levoleucovorin Calcium (6, 20 or 60 mg/kg/day; i.v.; for 4 weeks) enhances the toxicity of 5-Fluorouracil. |
|---|---|---|
| Animal model | Crj:CD(SD)BR rats (5 weeks) | |
| Dosages | 6, 20 or 60 mg/kg/day | |
| Administration | i.v.; for 4 weeks (combined with 10 mg/kg/day 5-Fluorouracil) |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9550 mL | 9.7752 mL | 19.5503 mL | 39.1007 mL |
| 5mM | 0.3910 mL | 1.9550 mL | 3.9101 mL | 7.8201 mL |
| 10mM | 0.1955 mL | 0.9775 mL | 1.9550 mL | 3.9101 mL |
| 20mM | 0.0978 mL | 0.4888 mL | 0.9775 mL | 1.9550 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.