Pemetrexed disodium heptahydrate (LY231514; HSDB7316; LY-231514; HSDB-7316; Alimta), the heptahydrated disodium salt of Pemetrexed and a pyrimidine-based antifolate, is an antifolate and antimetabolite anticancer medication.

Calcium Levofolinate (also known as Calcium Folinate; Calcium levofolinate; CL307782), a calcium salt of and the enantiomerically active form of folinic acid, is widely used as an adjuvant in cancer chemotherapy, e.g.

Pemetrexed (LY-231514; LY231514; HSDB7316; HSDB-7316; trade name Alimta), a synthetic pyrimidine-based antifolate, is antimetabolite anticancer drug that inhibits TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.