Caffeic Acid Phenethyl Ester

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
500mg	$320	Check With Us
1g	$580	Check With Us
5g	$1470	Check With Us

: [email protected] [email protected]

Cat #: V0766 CAS #: 104594-70-9 Purity ≥ 98%

Description: Caffeic acid phenethyl ester (also called CAPE; BAF-IN-C09; 2-Phenylethyl Caffeate; β-Phenylethyl Caffeate), a naturally occuring compound isolated from honeybee hive propolis, is potent and specific inhibitor of NF-κB activation with antioxidant, anticancer, immunomodulatory and antiinflammatory activities.

References: Lin HP, et al. Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1. Oncotarget. 2015 Mar 30;6(9):6684-707.

Top Publications Citing Invivochem Products

Product Catalog 2022

Guide to Product Handling

Publications Citing InvivoChem Products

Product Promise

Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	284.31
Molecular Formula	C17H16O4
CAS No.	104594-70-9
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 57 mg/mL (200.5 mM)r
	Water: <1 mg/mLr
	Ethanol: 57 mg/mL (200.5 mM)
SMILES Code	O=C(OCCC1=CC=CC=C1)/C=C/C2=CC=C(O)C(O)=C2
Synonyms	CAPE, Phenylethyl Caffeate; CAPE; Caffeic Acid Phenethyl Ester; BAF-IN-C09; 2-Phenylethyl Caffeate; β-Phenylethyl Caffeate;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.5173 mL	17.5864 mL	35.1729 mL	70.3457 mL
5mM	0.7035 mL	3.5173 mL	7.0346 mL	14.0691 mL
10mM	0.3517 mL	1.7586 mL	3.5173 mL	7.0346 mL
20mM	0.1759 mL	0.8793 mL	1.7586 mL	3.5173 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.