Cabazitaxel-d6 (TXD 258)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1875 | Check With Us |
| 200mg | $2810 | Check With Us |
| 500mg | $4740 | Check With Us |
: Cat #: V10500 CAS #: 1383561-29-2 Purity ≥ 98%
Description: Cabazitaxel-d6 is a deuterate form of cabazitaxel.
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- Physicochemical and Storage Information
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| Molecular Weight (MW) | 841.97 |
|---|---|
| Molecular Formula | C45H51D6NO14 |
| CAS No. | 1383561-29-2 |
| SMILES Code | O=C(O[C@@H]([C@@]1([H])[C@@]2(C)[C@@H](OC([2H])([2H])[2H])C[C@H]3OC[C@]31OC(C)=O)[C@]4(O)C[C@H](OC([C@H](O)[C@@H](NC(OC(C)(C)C)=O)C5=CC=CC=C5)=O)C(C)=C(C4(C)C)[C@@H](OC([2H])([2H])[2H])C2=O)C6=CC=CC=C6 |
| Synonyms | dimethoxydocetaxeld-6; deuteriumlabeled cabazitaxel. |
| Protocol | In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.1877 mL | 5.9385 mL | 11.8769 mL | 23.7538 mL |
| 5mM | 0.2375 mL | 1.1877 mL | 2.3754 mL | 4.7508 mL |
| 10mM | 0.1188 mL | 0.5938 mL | 1.1877 mL | 2.3754 mL |
| 20mM | 0.0594 mL | 0.2969 mL | 0.5938 mL | 1.1877 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.