Bruceine D
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $810 | Check With Us |
| 200mg | $1215 | Check With Us |
| 500mg | $2050 | Check With Us |
: Cat #: V17150 CAS #: 21499-66-1 Purity ≥ 99%
Description: Bruceine D is a novel and potent inhibitor of hepatocellular carcinoma growth.
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| Molecular Weight (MW) | 410.42 |
|---|---|
| Molecular Formula | C20H26O9 |
| CAS No. | 21499-66-1 |
| SMILES Code | CC([C@H](C[C@@H](O1)[C@]23C4[C@@H](O)[C@H](O)[C@](OC3)(C)[C@]2(O)[C@@H](O)C1=O)[C@]4(C)[C@@H]5O)=CC5=O |
| Synonyms | Bruceine D; Bruceine-D; |
| Protocol | In Vitro | Bruceine D (0.125-1.0 μM) dose-dependently promotes chromatin condensation, Annexin V-positive cell population and caspase-dependent apoptosis in H460 and A549 cells. Bruceine D inhibits the cell viability of H460 and A549 cells in a dose-dependent manner with IC50 values of 0.5 and 0.6 μM, respectively, at 48 h of treatment. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.4365 mL | 12.1826 mL | 24.3653 mL | 48.7306 mL |
| 5mM | 0.4873 mL | 2.4365 mL | 4.8731 mL | 9.7461 mL |
| 10mM | 0.2437 mL | 1.2183 mL | 2.4365 mL | 4.8731 mL |
| 20mM | 0.1218 mL | 0.6091 mL | 1.2183 mL | 2.4365 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.