Brimonidine Tartrate (UK 14304; AGN190342)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $650 | Check With Us |
| 5g | $1050 | Check With Us |
| 10g | $1575 | Check With Us |
: Cat #: V1105 CAS #: 70359-46-5 Purity ≥ 98%
Description: Brimonidine Tartrate (AGN-190342; UK14304; UK-14304; Alphagan), the tartrate salt of Brimonidine, is a highly potent and selective α-adrenergic receptor agonist with anti-hypertensive effects.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 442.22 |
|---|---|
| Molecular Formula | C15H16BrN5O6 |
| CAS No. | 70359-46-5 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 88 mg/mL (199 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 75 mg/mL (169.6 mM) | |
| Synonyms | AGN 190342; UK 14304; UK14304; Alphagan; AGN-190342; AGN190342; UK 14,304-18; UK 14,304; UK-14304; UK-14,304-18; UK-14,308 |
| Protocol | In Vitro | [3H]Brimonidine (UK 14304) is a full agonist at alpha 2-adrenergic receptors. [3H]Brimonidine (UK 14304) labels at least 2 specific binding sites in human brain that both have the characteristics of an alpha 2-adrenergic binding site. GTP decreases agonist binding at both of these sites, but with different potencies at each site [1-3]. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2613 mL | 11.3066 mL | 22.6132 mL | 45.2264 mL |
| 5mM | 0.4523 mL | 2.2613 mL | 4.5226 mL | 9.0453 mL |
| 10mM | 0.2261 mL | 1.1307 mL | 2.2613 mL | 4.5226 mL |
| 20mM | 0.1131 mL | 0.5653 mL | 1.1307 mL | 2.2613 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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Volume(start)
V1
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C2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.