Blonanserin (AD-5423)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10mg | $60 | 3-6 Days |
| 25mg | $90 | 3-6 Days |
| 50mg | $138 | 3-6 Days |
| 100mg | $218 | 3-6 Days |
| 250mg | $399 | 3-6 Days |
| 500mg | $650 | 3-6 Days |
| 1g | $980 | 3-6 Days |
: Cat #: V1021 CAS #: 132810-10-7 Purity ≥ 98%
Description: Blonanserin (formerly AD 5423; AD-5423; AD5423) is an atypical antipsychotic agent acting as a relatively selective serotonin (5-HT)2A and dopamine D2 antagonist with the potential to be used for the treatment of schizophrenia.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 367.5 |
|---|---|
| Molecular Formula | C23H30FN3 |
| CAS No. | 132810-10-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: N/Ar |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| Synonyms | AD 5423; AD-5423; AD5423; |
| Protocol | In Vivo | Blonanserin (oral gavage; 1 mg/kg; 14 days) significantly ameliorates the social deficit observed in PCP-administered mice and inhibits the decrease in the levels of Ser897-phosphorylation, but preatment with blonanserin does not affect the social behaviors in saline-administered mice |
|---|---|---|
| Animal model | Mice received saline or phencyclidine once a day for 14 consecutive days | |
| Dosages | 1 mg/kg | |
| Administration | Oral gavage; 1 mg/kg; 14 days |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.7211 mL | 13.6054 mL | 27.2109 mL | 54.4218 mL |
| 5mM | 0.5442 mL | 2.7211 mL | 5.4422 mL | 10.8844 mL |
| 10mM | 0.2721 mL | 1.3605 mL | 2.7211 mL | 5.4422 mL |
| 20mM | 0.1361 mL | 0.6803 mL | 1.3605 mL | 2.7211 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.