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| Size | Price | Stock |
|---|---|---|
| 25mg | $90 | 3-6 Days |
| 50mg | $140 | 3-6 Days |
| 100mg | $200 | 3-6 Days |
| 250mg | $340 | 3-6 Days |
| 500mg | $500 | 3-6 Days |
: Cat #: V29332 CAS #: 78186-34-2 Purity ≥ 99%
Description: Bisantrene (CL 216942; NSC 337766) is potent inhibitor of topoisomerase II and DNA intercalators. It could be employed as model compounds to investigate multiple drug resistance (MDR1) mediated by P-glycoprotein. You could use bisantrene as a Rac1 inhibitor. DNA single-strand breaks, DNA-protein crosslinking, and the inhibition of DNA replication are all caused by bisantrene intercalating with DNA and altering its configuration. In terms of activity, this agent is comparable to doxorubicin; however, it does not show cardiotoxicity.
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| Molecular Weight (MW) | 398.46 |
|---|---|
| Molecular Formula | C₂₂H₂₂N₈ |
| CAS No. | 78186-34-2 |
| Storage | Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Synonyms | Bisantrene; CL216942 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5097 mL | 12.5483 mL | 25.0966 mL | 50.1932 mL |
| 5mM | 0.5019 mL | 2.5097 mL | 5.0193 mL | 10.0386 mL |
| 10mM | 0.2510 mL | 1.2548 mL | 2.5097 mL | 5.0193 mL |
| 20mM | 0.1255 mL | 0.6274 mL | 1.2548 mL | 2.5097 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.