Bergenin (Cuscutin)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $360 | Check With Us |
| 5g | $1120 | Check With Us |
| 10g | $1680 | Check With Us |
: Cat #: V1981 CAS #: 477-90-7 Purity ≥ 98%
Description: Bergenin (Cuscutin) is a natural isocoumarin found in various medicinal plants.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 328.27 |
|---|---|
| Molecular Formula | C14H16O9 |
| CAS No. | 477-90-7 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: > 10 mMr |
| Water: NAr | |
| Ethanol: NA | |
| SMILES Code | O=C1C2=C(C(O)=C(OC)C(O)=C2)[C@@]3([H])[C@]([C@@H](O)[C@H](O)[C@@H](CO)O3)([H])O1 |
| Synonyms | Cuscutin |
| Protocol | In Vitro | Bergenin (7.5-30 µM; 24 hours) induces apoptosis in HeLa cervical cancer cells. Bergenin (7.5-30µM; 24 hours) decreases the viability of HeLa cervical cancer cells (IC50=15 µM). |
|---|---|---|
| In Vivo | Pretreatment with Bergenin (12.5-100 mg/kg; i.p.; once) produces a dose-related inhibition of acetic acid-induced writhing in mice. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.0463 mL | 15.2314 mL | 30.4627 mL | 60.9255 mL |
| 5mM | 0.6093 mL | 3.0463 mL | 6.0925 mL | 12.1851 mL |
| 10mM | 0.3046 mL | 1.5231 mL | 3.0463 mL | 6.0925 mL |
| 20mM | 0.1523 mL | 0.7616 mL | 1.5231 mL | 3.0463 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.