BD 1047 dihydrobromide

This product is for research use only, not for human use. We do not sell to patients.

BD 1047 dihydrobromide
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$850Check With Us
500mg$1400Check With Us
1g$2100Check With Us

Cat #: V2985 CAS #: 138356-21-5 Purity ≥ 98%

Description: BD1047 dihydrobromide (BD-1047) is a selective functional antagonist of sigma receptors (σ receptors) with antipsychotic activity and may be used for schizophrenia.

References: Shimazawa M, et al. Effect of a sigma-1 receptor agonist, cutamesine dihydrochloride (SA4503), on photoreceptor cell death against light-induced damage. Exp Eye Res. 2015 Mar;132:64-72.

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Molecular Weight (MW)437.04
Molecular FormulaC13H20Cl2N2.2HBr
CAS No.138356-21-5
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: ≥ 36 mg/mLrr
Water: <1 mg/mLrr
Ethanol: <1 mg/mL
SMILES CodeCN(CCN(CCC1=CC=C(Cl)C(Cl)=C1)C)C.[H]Br.[H]Br
SynonymsBD-1047 HBr; BD-1047 diHBr; BD-1047; BD 1047; BD1047;
ProtocolIn VitroBD-1047 (dihydrobromide) prevents that Cutamesine reduces the cell death rate induced by light exposure in murine photoreceptor-derived 661w cells
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.2881 mL11.4406 mL22.8812 mL45.7624 mL
5mM0.4576 mL2.2881 mL4.5762 mL9.1525 mL
10mM0.2288 mL1.1441 mL2.2881 mL4.5762 mL
20mM0.1144 mL0.5720 mL1.1441 mL2.2881 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.