BA-53038B
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1250 | To Be Confirmed |
| 200mg | $1875 | To Be Confirmed |
| 500mg | $3165 | To Be Confirmed |
: Cat #: V24024 CAS #: 2306195-65-1 Purity ≥ 99%
Description: BA-53038B (BA53038B)is a novel and potent Hepatitis B Virus Nucleocapsid Assembly Inhibitor, also called HBV core protein allosteric modulator (CpAM).
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- Related Biological Data
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| Molecular Weight (MW) | 249.74 |
|---|---|
| Molecular Formula | C14H16ClNO |
| CAS No. | 2306195-65-1 |
| Synonyms | BA-53038B; BA53038B; BA 53038B; |
| Protocol | In Vitro | BA-53038B has antiviral activity for HBV with an EC50 value of 3.32 μM. BA-53038B (5 μM; 48 h) induces the capsid/nucleocapsid mobility shift and reduced the amount of hypophosphorylated core protein. BA-53038B has cytotoxicity with CC50 value of >100 μM. BA-53038B (5 μM; 2 days) inhibits pgRNA encapsidation and consequentially reduces the amount of DNA-containing capsids and hypophosphorylated core protein. BA-53038B has resistant effect with an EC50 value of >10 μM on HBV capsid (HepG2 cells transiently transfected pHBV1.3/core-V124W). BA-53038B (0-20 μM; 2 or 6 days) inhibits HBV nucleocapsid assembly. BA-53038B (2 μM; 6 h) modulates HBV capsid assembly by binding to the HAP pocket. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.0042 mL | 20.0208 mL | 40.0416 mL | 80.0833 mL |
| 5mM | 0.8008 mL | 4.0042 mL | 8.0083 mL | 16.0167 mL |
| 10mM | 0.4004 mL | 2.0021 mL | 4.0042 mL | 8.0083 mL |
| 20mM | 0.2002 mL | 1.0010 mL | 2.0021 mL | 4.0042 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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The dilution calculator equation
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Volume(start)
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.