Morphothiadin (formerly GLS-4; GLS4) is a novel, potent and selective inhibitor of HBV replication, effective against both wild-type and adefovir-resistant HBV with an IC50 of 12 nM.

Isoscopoletin is a novel and potent bioactive compound.

RG7834 S-isomer, also known as RO 7020322 is the S-enantiomer of RG7834 (RO-7020322) which is a novel, potent and orally bioavailable inhibitor of HBV viral gene expression which blocks viral antigen and virion production. RG7834 is highly selective for HBV, and has a unique antiviral profile that is clearly differentiated from nucleos(t)ide analogues. RG7834 (also […]

Torcitabine (2′-Deoxy-L-cytidine) is a novel and potent antiviral agent against hepatitis B virus.

4,5-Dicaffeoylquinic acid is a novel and potent hepatoprotective and anti-HBV effects.

Bulevirtide (Myrcludex B; MyrB; Hepcludex) is a first-in-class entry inhibitor approved as an antiviral medication for the treatment of chronic hepatitis D.

AB-423, a member of the sulfamoylbenzamide (SBA) class, is a potent HBV (hepatitis B virus) capsid assembly inhibitor that inhibits HBV replication with EC50/EC90 of 0.08-0.27 μM/0.33-1.32 μM in cells. AB-423 is currently under phase 1 clinical trials. AB-423 inhibited HBV genotypes A through D and nucleos(t)ide-resistant variants in vitro Treatment of HepDES19 cells with […]

BAY 41-4109 racemate is the racemic mixture of BAY 41-4109 which is a novel and potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.

BAY 41-4109 is a novel and potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.

Bay 41-4109 S-isomer is the less active enantiomer of Bay 41-4109.