AZD1080
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1090 | Check With Us |
| 500mg | $1690 | Check With Us |
| 1g | $2535 | Check With Us |
: Cat #: V0220 CAS #: 612487-72-6 Purity ≥ 98%
Description: AZD1080 is a selective, potent, orally bioactive, and brain permeable GSK3 (glycogen synthase kinase-3) inhibitor with neuroprotective effects.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 334.37 |
|---|---|
| Molecular Formula | C19H18N4O2 |
| CAS No. | 612487-72-6 |
| Solubility In Vitro | DMSO: 52 mg/mL (155.5 mM) r |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| Solubility In Vivo | 30% PEG400+0.5% Tween80+5% propylene glycol: 20 mg/mL |
| SMILES Code | N#CC1=CC2=C(NC(/C2=C3C=CC(CN4CCOCC4)=CN/3)=O)C=C1 |
| Synonyms | AZD-1080; AZD 1080; AZD-1080 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.9907 mL | 14.9535 mL | 29.9070 mL | 59.8140 mL |
| 5mM | 0.5981 mL | 2.9907 mL | 5.9814 mL | 11.9628 mL |
| 10mM | 0.2991 mL | 1.4953 mL | 2.9907 mL | 5.9814 mL |
| 20mM | 0.1495 mL | 0.7477 mL | 1.4953 mL | 2.9907 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.