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Atomoxetine HCl (Tomoxetine; LY 139603)

This product is for research use only, not for human use. We do not sell to patients.

Atomoxetine HCl (Tomoxetine; LY 139603)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$800Check With Us
5g$1350Check With Us
10g$2025Check With Us
email: [email protected]        [email protected]

Cat #: V1023 CAS #: 82248-59-7 Purity ≥ 98%

Description: Atomoxetine HCl (formerly LY139603; LY-139603; Tomoxetine; Strattera; Tomoxetina; Tomoxetinum), the hydrochloride salt of Atomoxetine, is a potent and selective norepinephrine (NE) transporter/reuptate inhibitor that has been used for treating attention-deficit hyperactivity disorder (ADHD).

References: McAfee AT, Landon J, Jones M, et al. A cohort study of the risk of seizures in a pediatric population treated with atomoxetine or stimulant medications. Pharmacoepidemiol Drug Saf. 2012 Dec 26.

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Molecular Weight (MW)291.82
Molecular FormulaC17H21NO.HCl
CAS No.82248-59-7
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 58 mg/mL (198.8 mM)r
Water: 2 mg/mL (6.8 mM)r
Ethanol: 37 mg/mL (126.8 mM)
SynonymsLY 139603 HCl; LY-139603 HCl; Atomoxetine; LY139603 HCl; Tomoxetine; Tomoxetina; Tomoxetinum; (-)-Tomoxetine; Strattera; Tomoxetine hydrochloride; LY 139603; (R)-Tomoxetine hydrochloride
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.4268 mL17.1338 mL34.2677 mL68.5354 mL
5mM0.6854 mL3.4268 mL6.8535 mL13.7071 mL
10mM0.3427 mL1.7134 mL3.4268 mL6.8535 mL
20mM0.1713 mL0.8567 mL1.7134 mL3.4268 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.