ARN2966

This product is for research use only, not for human use. We do not sell to patients.

ARN2966
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1020Check With Us
500mg$1480Check With Us
1g$2220Check With Us

Cat #: V4637 CAS #: 102212-26-0 Purity ≥ 98%

Description: ARN2966 is a novel and potent post-transcriptional modulator of APP (amyloid precursor protein) expression; reduces expression of APP with resultant lower production of Aβ.

References: yodeji Asuni, et al. An APP translation modulator ARN2966 reduces BETA-AMYLOID deposition and prevents memory deficits in ALZHEIMER'S DISEASE transgenic mice. Alzheimer's & Dementia: The Journal of the Alzheimer's Association. 2012.

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Product Promise

Promise
Molecular Weight (MW)200.24
Molecular FormulaC₁₂H₁₂N₂O
CAS No.102212-26-0
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
SMILES CodeOC1=CC=CC=C1NCC2=NC=CC=C2
Synonyms ARN-2966; ARN 2966; ARN2966; 2-PMAP; 2 PMAP
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.9940 mL24.9700 mL49.9401 mL99.8801 mL
5mM0.9988 mL4.9940 mL9.9880 mL19.9760 mL
10mM0.4994 mL2.4970 mL4.9940 mL9.9880 mL
20mM0.2497 mL1.2485 mL2.4970 mL4.9940 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.